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Alpha or beta human chorionic gonadotropin knockdown decrease BeWo cell fusion by down-regulating PKA and CREB activation

The aim of the present study is to delineate the role of human chorionic gonadotropin (hCG) in trophoblast fusion. In this direction, using shRNA lentiviral particles, α- and β-hCG silenced ‘BeWo’ cell lines were generated. Treatment of both α- and β-hCG silenced BeWo cells with either forskolin or...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Saryu Malhotra, Sudha, Suman, Pankaj, Kumar Gupta, Satish
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459146/
https://ncbi.nlm.nih.gov/pubmed/26053549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11210
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