Structural apelin analogues: mitochondrial ROS inhibition and cardiometabolic protection in myocardial ischaemia reperfusion injury

BACKGROUND AND PURPOSE: Mitochondria-derived oxidative stress is believed to be crucially involved in cardiac ischaemia reperfusion (I/R) injury, although currently no therapies exist that specifically target mitochondrial reactive oxygen species (ROS) production. The present study was designed to e...

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Bibliographic Details
Published in:Br J Pharmacol
Main Authors: Pisarenko, Oleg, Shulzhenko, Valentin, Studneva, Irina, Pelogeykina, Yulia, Timoshin, Alexander, Anesia, Rodica, Valet, Philippe, Parini, Angelo, Kunduzova, Oksana
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2015
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459014/
https://ncbi.nlm.nih.gov/pubmed/25521429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13038
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