Preclinical Assessment of Lisdexamfetamine as an Agonist Medication Candidate for Cocaine Addiction: Effects in Rhesus Monkeys Trained to Discriminate Cocaine or to Self-Administer Cocaine in a Cocaine Versus Food Choice Procedure

BACKGROUND: Chronic amphetamine treatment decreases cocaine consumption in preclinical and human laboratory studies and in clinical trials. Lisdexamfetamine is an amphetamine prodrug in which L-lysine is conjugated to the terminal nitrogen of d-amphetamine. Prodrugs may be advantageous relative to t...

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Veröffentlicht in:Int J Neuropsychopharmacol
Hauptverfasser: Banks, Matthew L., Hutsell, Blake A., Blough, Bruce E., Poklis, Justin L., Negus, S. Stevens
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458439/
https://ncbi.nlm.nih.gov/pubmed/25618405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv009
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