Genetic variation in Surfactant Protein-A2 (SP-A2) leads to differential binding to Mycoplasma pneumoniae membranes and regulation of host responses

Mycoplasma pneumoniae (Mp) is an extracellular pathogen that colonizes mucosal surfaces of the respiratory tract and is associated with asthma exacerbations. Previous reports demonstrate that surfactant protein-A (SP-A) binds live Mp and mycoplasma membranes (MMF) with high affinity. Humans express...

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Publicado en:J Immunol
Main Authors: Ledford, Julie G., Voelker, Dennis R., Addison, Kenneth J., Wang, Ying, Nikam, Vinayak, Degan, Simone, Kandasamy, Pitachaimani, Tanyaratsrisakul, Sasipa, Fischer, Bernard M., Kraft, Monica, Hollingsworth, John W.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458406/
https://ncbi.nlm.nih.gov/pubmed/25957169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500104
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