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Selenocysteine incorporation: A trump card in the game of mRNA decay

The incorporation of the 21st amino acid, selenocysteine (Sec), occurs on mRNAs that harbor in-frame stop codons because the Sec-tRNA(Sec) recognizes a UGA codon. This sets up an intriguing interplay between translation elongation, translation termination and the complex machinery that marks mRNAs t...

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Bibliografiske detaljer
Udgivet i:Biochimie
Main Authors: Shetty, Sumangala P., Copeland, Paul R.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458392/
https://ncbi.nlm.nih.gov/pubmed/25622574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2015.01.007
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