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Absolute Quantitation of Glycosylation Site Occupancy Using Isotopically Labeled Standards and LC-MS

N-linked glycans are required to maintain appropriate biological functions on proteins. Underglycosylation leads to many diseases in plants and animals; therefore, characterizing the extent of glycosylation on proteins is an important step in understanding, diagnosing, and treating diseases. To dete...

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Bibliographic Details
Published in:J Am Soc Mass Spectrom
Main Authors: Zhu, Zhikai, Go, Eden P., Desaire, Heather
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458369/
https://ncbi.nlm.nih.gov/pubmed/24671695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-014-0859-2
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