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Ceramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ Accumulation

Alzheimer's disease (AD), the most common chronic and progressive neurodegenerative disorder, is characterized by extracellular deposits of amyloid β-peptides (Aβ) and intracellular deposits of hyperphosphorylated tau (phospho-tau) protein. Ceramides, the major molecules of sphingolipid metabol...

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Publicat a:Oxid Med Cell Longev
Autors principals: Jazvinšćak Jembrek, Maja, Hof, Patrick R., Šimić, Goran
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458271/
https://ncbi.nlm.nih.gov/pubmed/26090071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/346783
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