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Global Promotion of Alternative Internal Exon Usage by mRNA 3’-End Formation Factors

The mechanisms that regulate alternative pre-mRNA splicing are largely unknown. Here we perform an RNA interference screen to identify factors required for alternative splicing regulation by RBFOX2, an RNA-binding protein that promotes either exon inclusion or exclusion. Unexpectedly, we find that t...

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Publicado en:Mol Cell
Autores principales: Misra, Ashish, Ou, Jianhong, Zhu, Lihua J., Green, Michael R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458236/
https://ncbi.nlm.nih.gov/pubmed/25921069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.03.016
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