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A Protein Kinase C phosphorylation motif in GLUT1 affects glucose transport and is mutated in GLUT1 deficiency syndrome

Protein Kinase C has been implicated in the phosphorylation of the erythrocyte/brain glucose transporter, GLUT1, without a clear understanding of the site(s) of phosphorylation and the possible effects on glucose transport. Through in-vitro kinase assays, mass spectrometry, and phosphospecific antib...

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Vydáno v:Mol Cell
Hlavní autoři: Lee, Eunice E., Ma, Jing, Sacharidou, Anastasia, Mi, Wentao, Salato, Valerie K., Nguyen, Nam, Jiang, Youxing, Pascual, Juan M., North, Paula E., Shaul, Philip W., Mettlen, Marcel, Wang, Richard C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458224/
https://ncbi.nlm.nih.gov/pubmed/25982116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.04.015
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