Intravesical chitosan/interleukin-12 immunotherapy induces tumor-specific systemic immunity against murine bladder cancer

Bladder cancer is a highly recurrent disease in need of novel, durable treatment strategies. This study assessed the ability of an intravesical immunotherapy composed of a coformulation of the biopolymer chitosan with interleukin-12 (CS/IL-12) to induce systemic adaptive tumor-specific immunity. Int...

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Udgivet i:Cancer Immunol Immunother
Main Authors: Smith, Sean G., Koppolu, Bhanu prasanth, Ravindranathan, Sruthi, Kurtz, Samantha L., Yang, Lirong, Katz, Matthew D., Zaharoff, David A.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2015
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458215/
https://ncbi.nlm.nih.gov/pubmed/25754122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-015-1672-x
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