Robust axonal regeneration occurs in the injured CAST/Ei mouse central nervous system

Axon regeneration in the central nervous system (CNS) requires reactivating injured neurons’ intrinsic growth state and enabling growth in an inhibitory environment. Using an inbred mouse neuronal phenotypic screen, we find that CAST/Ei mouse adult dorsal root ganglion neurons extend axons more on C...

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Gepubliceerd in:Neuron
Hoofdauteurs: Omura, Takao, Omura, Kumiko, Tedeschi, Andrea, Riva, Priscilla, Painter, Michio W, Rojas, Leticia, Martin, Joshua, Lisi, Véronique, Huebner, Eric A, Latremoliere, Alban, Yin, Yuqin, Barrett, Lee, Singh, Bhagat, Lee, Stella, Crisman, Tom, Gao, Fuying, Li, Songlin, Kapur, Kush, Geschwind, Daniel H, Kosik, Kenneth S, Coppola, Giovanni, He, Zhigang, Carmichael, S Thomas, Benowitz, Larry I, Costigan, Michael, Woolf, Clifford J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458182/
https://ncbi.nlm.nih.gov/pubmed/26004914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.05.005
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