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Epigenetic modifications and long non-coding RNAs influence pancreas development and function

Insulin-producing β-cells within the pancreatic islet of Langerhans are responsible for maintaining glucose homeostasis; the loss or malfunction of β-cells results in diabetes mellitus. Recent advances in cell purification strategies and sequencing technologies as well as novel molecular tools have...

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Detalhes bibliográficos
Publicado no:Trends Genet
Main Authors: Arnes, Luis, Sussel, Lori
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458180/
https://ncbi.nlm.nih.gov/pubmed/25812926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2015.02.008
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