Inhibition of NOS-NO System Prevents Autoimmune Orchitis Development in Rats: Relevance of NO Released by Testicular Macrophages in Germ Cell Apoptosis and Testosterone Secretion

BACKGROUND: Although the testis is considered an immunoprivileged organ it can orchestrate immune responses against pathological insults such as infection and trauma. Experimental autoimmune orchitis (EAO) is a model of chronic inflammation whose main histopathological features it shares with human...

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Udgivet i:PLoS One
Main Authors: Jarazo Dietrich, Sabrina, Fass, Mónica Irina, Jacobo, Patricia Verónica, Sobarzo, Cristian Marcelo Alejandro, Lustig, Livia, Theas, María Susana
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457887/
https://ncbi.nlm.nih.gov/pubmed/26046347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128709
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