Lack of the Lysosomal Membrane Protein, GLMP, in Mice Results in Metabolic Dysregulation in Liver

Ablation of glycosylated lysosomal membrane protein (GLMP, formerly known as NCU-G1) has been shown to cause chronic liver injury which progresses into liver fibrosis in mice. Both lysosomal dysfunction and chronic liver injury can cause metabolic dysregulation. Glmp(gt/gt) mice (formerly known as N...

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發表在:PLoS One
Main Authors: Kong, Xiang Yi, Kase, Eili Tranheim, Herskedal, Anette, Schjalm, Camilla, Damme, Markus, Nesset, Cecilie Kasi, Thoresen, G. Hege, Rustan, Arild C., Eskild, Winnie
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457871/
https://ncbi.nlm.nih.gov/pubmed/26047317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129402
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