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Induction of Apoptosis in MCF-7 Cells via Oxidative Stress Generation, Mitochondria-Dependent and Caspase-Independent Pathway by Ethyl Acetate Extract of Dillenia suffruticosa and Its Chemical Profile

Dillenia suffruticosa, which is locally known as Simpoh air, has been traditionally used to treat cancerous growth. The ethyl acetate extract of D. suffruticosa (EADs) has been shown to induce apoptosis in MCF-7 breast cancer cells in our previous study. The present study aimed to elucidate the mole...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Tor, Yin Sim, Yazan, Latifah Saiful, Foo, Jhi Biau, Wibowo, Agustono, Ismail, Norsharina, Cheah, Yoke Kqueen, Abdullah, Rasedee, Ismail, Maznah, Ismail, Intan Safinar, Yeap, Swee Keong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457850/
https://ncbi.nlm.nih.gov/pubmed/26047480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127441
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