Expression of HIF-1α and Markers of Angiogenesis Are Not Significantly Different in Triple Negative Breast Cancer Compared to Other Breast Cancer Molecular Subtypes: Implications for Future Therapy

INTRODUCTION: Triple negative breast cancer lacks estrogen, progesterone and epidermal growth factor receptors rendering it refractory to available targetedtherapies. TNBC is associated with central fibrosis and necrosis, both indicators of tumor hypoxia. Hypoxia inducible factor 1α is up-regulated...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yehia, Lamis, Boulos, Fouad, Jabbour, Mark, Mahfoud, Ziyad, Fakhruddin, Najla, El-Sabban, Marwan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457831/
https://ncbi.nlm.nih.gov/pubmed/26046764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129356
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