Classification of Epidermal Growth Factor Receptor Gene Mutation Status Using Serum Proteomic Profiling Predicts Tumor Response in Patients with Stage IIIB or IV Non-Small-Cell Lung Cancer

OBJECTIVES: Epidermal growth factor receptor (EGFR) gene mutations in tumors predict tumor response to EGFR tyrosine kinase inhibitors (EGFR-TKIs) in non-small-cell lung cancer (NSCLC). However, obtaining tumor tissue for mutation analysis is challenging. Here, we aimed to detect serum peptides/prot...

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Vydáno v:PLoS One
Hlavní autoři: Yang, Lin, Tang, Chuanhao, Xu, Bin, Wang, Weixia, Li, Jianjie, Li, Xiaoyan, Qin, Haifeng, Gao, Hongjun, He, Kun, Song, Santai, Liu, Xiaoqing
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457791/
https://ncbi.nlm.nih.gov/pubmed/26047516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128970
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