IQ Motif-Containing GTPase-Activating Protein 2 (IQGAP2) Is a Novel Regulator of Colonic Inflammation in Mice

IQ motif-containing GTPase-activating protein 2 (IQGAP2) is a multidomain scaffolding protein that plays a role in cytoskeleton regulation by juxtaposing Rho GTPase and Ca(2+)/calmodulin signals. While IQGAP2 suppresses tumorigenesis in liver, its role in pathophysiology of the gastrointestinal trac...

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Publicado en:PLoS One
Main Authors: Ghaleb, Amr M., Bialkowska, Agnieszka B., Snider, Ashley J., Gnatenko, Dmitri V., Hannun, Yusuf A., Yang, Vincent W., Schmidt, Valentina A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457730/
https://ncbi.nlm.nih.gov/pubmed/26047140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129314
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