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Decreased Dicer expression is linked to increased expression of co-stimulatory molecule CD80 on B cells in Multiple Sclerosis

BACKGROUND: MS is an immune-mediated inflammatory disease of the CNS. B cells have been strongly implicated in disease pathogenesis based on clinical trials with B cell ablation. There is a growing body of evidence linking microRNAs with regulation of the immune system. Dicer, a key enzyme involved...

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Bibliografiske detaljer
Udgivet i:Mult Scler
Main Authors: Aung, Latt Latt, Balashov, Konstantin E.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457720/
https://ncbi.nlm.nih.gov/pubmed/25480859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1352458514560923
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