Basement membrane protein nidogen-1 is a target of meprin β in cisplatin nephrotoxicity

Meprins are oligomeric metalloproteinases that are abundantly expressed in the brush-border membranes of renal proximal tubules. During acute kidney injury (AKI) induced by cisplatin or ischemia-reperfusion, membrane-bound meprins are shed and their localization is altered from the apical membranes...

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Bibliographic Details
Published in:Toxicol Lett
Main Authors: Herzog, Christian, Marisiddaiah, Raju, Haun, Randy S., Kaushal, Gur P.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457671/
https://ncbi.nlm.nih.gov/pubmed/25957482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2015.05.005
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