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NRMT1 knockout mice exhibit phenotypes associated with impaired DNA repair and premature aging

Though defective genome maintenance and DNA repair have long been know to promote phenotypes of premature aging, the role protein methylation plays in these processes is only now emerging. We have recently identified the first N-terminal methyltransferase, NRMT1, which regulates protein-DNA interact...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mech Ageing Dev
मुख्य लेखकों: Bonsignore, Lindsay A., Tooley, John G., Van Hoose, Patrick M., Wang, Eugenia, Cheng, Alan, Cole, Marsha P., Tooley, Christine E. Schaner
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457563/
https://ncbi.nlm.nih.gov/pubmed/25843235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2015.03.012
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