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Retrograde NGF Axonal Transport—Motor Coordination in the Unidirectional Motility Regime

We present a detailed motion analysis of retrograde nerve growth factor (NGF) endosomes in axons to show that mechanical tugs-of-war and intracellular motor regulation are complimentary features of the near-unidirectional endosome directionality. We used quantum dots to fluorescently label NGF and a...

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Pubblicato in:Biophys J
Autori principali: Chowdary, Praveen D., Che, Daphne L., Zhang, Kai, Cui, Bianxiao
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457490/
https://ncbi.nlm.nih.gov/pubmed/26039170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.04.036
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