Different KChIPs Compete for Heteromultimeric Assembly with Pore-Forming Kv4 Subunits

Auxiliary Kv channel-interacting proteins 1–4 (KChIPs1–4) coassemble with pore-forming Kv4 α-subunits to form channel complexes underlying somatodendritic subthreshold A-type current that regulates neuronal excitability. It has been hypothesized that different KChIPs can competitively bind to Kv4 α-...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Zhou, Jingheng, Tang, Yiquan, Zheng, Qin, Li, Meng, Yuan, Tianyi, Chen, Liangyi, Huang, Zhuo, Wang, KeWei
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Channels and Transporters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457479/
https://ncbi.nlm.nih.gov/pubmed/26039167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.04.024
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