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Genetic encoding of the post-translational modification 2-hydroxyisobutyryl-lysine

We report the synthesis and genetic encoding of a recently discovered posttranslational modification, 2-hydroxyisobutryl-lysine, to the genetic code of E. coli. The production of homogeneous proteins containing this amino acid will facilitate the study of modification in full-length proteins.

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Knight, William A., Cropp, T. Ashton
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457286/
https://ncbi.nlm.nih.gov/pubmed/25999185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob00283d
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