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Genetic encoding of the post-translational modification 2-hydroxyisobutyryl-lysine

We report the synthesis and genetic encoding of a recently discovered posttranslational modification, 2-hydroxyisobutryl-lysine, to the genetic code of E. coli. The production of homogeneous proteins containing this amino acid will facilitate the study of modification in full-length proteins.

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Org Biomol Chem
Prif Awduron: Knight, William A., Cropp, T. Ashton
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457286/
https://ncbi.nlm.nih.gov/pubmed/25999185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob00283d
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