The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain

BACKGROUND: Tumour metastasis to the brain is a common and deadly development in certain cancers; 18–30 % of breast tumours metastasise to the brain. The contribution that gene silencing through epigenetic mechanisms plays in these metastatic tumours is not well understood. RESULTS: We have carried...

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Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Pangeni, Rajendra P., Channathodiyil, Prasanna, Huen, David S., Eagles, Lawrence W., Johal, Balraj K., Pasha, Dawar, Hadjistephanou, Natasa, Nevell, Oliver, Davies, Claire L., Adewumi, Ayobami I., Khanom, Hamida, Samra, Ikroop S., Buzatto, Vanessa C., Chandrasekaran, Preethi, Shinawi, Thoraia, Dawson, Timothy P., Ashton, Katherine M., Davis, Charles, Brodbelt, Andrew R., Jenkinson, Michael D., Bièche, Ivan, Latif, Farida, Darling, John L., Warr, Tracy J., Morris, Mark R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457099/
https://ncbi.nlm.nih.gov/pubmed/26052355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0089-x
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