The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain

BACKGROUND: Tumour metastasis to the brain is a common and deadly development in certain cancers; 18–30 % of breast tumours metastasise to the brain. The contribution that gene silencing through epigenetic mechanisms plays in these metastatic tumours is not well understood. RESULTS: We have carried...

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Bibliographic Details
Published in:Clin Epigenetics
Main Authors: Pangeni, Rajendra P., Channathodiyil, Prasanna, Huen, David S., Eagles, Lawrence W., Johal, Balraj K., Pasha, Dawar, Hadjistephanou, Natasa, Nevell, Oliver, Davies, Claire L., Adewumi, Ayobami I., Khanom, Hamida, Samra, Ikroop S., Buzatto, Vanessa C., Chandrasekaran, Preethi, Shinawi, Thoraia, Dawson, Timothy P., Ashton, Katherine M., Davis, Charles, Brodbelt, Andrew R., Jenkinson, Michael D., Bièche, Ivan, Latif, Farida, Darling, John L., Warr, Tracy J., Morris, Mark R.
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457099/
https://ncbi.nlm.nih.gov/pubmed/26052355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0089-x
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