The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain

BACKGROUND: Tumour metastasis to the brain is a common and deadly development in certain cancers; 18–30 % of breast tumours metastasise to the brain. The contribution that gene silencing through epigenetic mechanisms plays in these metastatic tumours is not well understood. RESULTS: We have carried...

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Gepubliceerd in:Clin Epigenetics
Hoofdauteurs: Pangeni, Rajendra P., Channathodiyil, Prasanna, Huen, David S., Eagles, Lawrence W., Johal, Balraj K., Pasha, Dawar, Hadjistephanou, Natasa, Nevell, Oliver, Davies, Claire L., Adewumi, Ayobami I., Khanom, Hamida, Samra, Ikroop S., Buzatto, Vanessa C., Chandrasekaran, Preethi, Shinawi, Thoraia, Dawson, Timothy P., Ashton, Katherine M., Davis, Charles, Brodbelt, Andrew R., Jenkinson, Michael D., Bièche, Ivan, Latif, Farida, Darling, John L., Warr, Tracy J., Morris, Mark R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457099/
https://ncbi.nlm.nih.gov/pubmed/26052355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0089-x
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