The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain

BACKGROUND: Tumour metastasis to the brain is a common and deadly development in certain cancers; 18–30 % of breast tumours metastasise to the brain. The contribution that gene silencing through epigenetic mechanisms plays in these metastatic tumours is not well understood. RESULTS: We have carried...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Pangeni, Rajendra P., Channathodiyil, Prasanna, Huen, David S., Eagles, Lawrence W., Johal, Balraj K., Pasha, Dawar, Hadjistephanou, Natasa, Nevell, Oliver, Davies, Claire L., Adewumi, Ayobami I., Khanom, Hamida, Samra, Ikroop S., Buzatto, Vanessa C., Chandrasekaran, Preethi, Shinawi, Thoraia, Dawson, Timothy P., Ashton, Katherine M., Davis, Charles, Brodbelt, Andrew R., Jenkinson, Michael D., Bièche, Ivan, Latif, Farida, Darling, John L., Warr, Tracy J., Morris, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457099/
https://ncbi.nlm.nih.gov/pubmed/26052355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0089-x
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