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Multi-layered molecular mechanisms of polypeptide holding, unfolding and disaggregation by HSP70/HSP110 chaperones

Members of the HSP70/HSP110 family (HSP70s) form a central hub of the chaperone network controlling all aspects of proteostasis in bacteria and the ATP-containing compartments of eukaryotic cells. The heat-inducible form HSP70 (HSPA1A) and its major cognates, cytosolic HSC70 (HSPA8), endoplasmic ret...

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Bibliografiske detaljer
Udgivet i:Front Mol Biosci
Main Authors: Finka, Andrija, Sharma, Sandeep K., Goloubinoff, Pierre
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456865/
https://ncbi.nlm.nih.gov/pubmed/26097841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2015.00029
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