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Efficient in vitro generation of functional thymic epithelial progenitors from human embryonic stem cells

Thymic epithelial cells (TECs) are the major components of the thymic microenvironment for T cell development. TECs are derived from thymic epithelial progenitors (TEPs). It has been reported that human ESCs (hESCs) can be directed to differentiate into TEPs in vitro. However, the efficiency for the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Su, Min, Hu, Rong, Jin, Jingjun, Yan, Yuan, Song, Yinhong, Sullivan, Ryan, Lai, Laijun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456731/
https://ncbi.nlm.nih.gov/pubmed/26044259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09882
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