Visualizing hippocampal synaptic function by optical detection of Ca2+ entry through the N-methyl-D-aspartate channel.

Fura-2 and imaging technology were used to detect intracellular Ca2+ changes in CA1 pyramidal cells in hippocampal slices. During focal synaptic stimulation, one or more highly localized regions of Ca2+ elevation (hot spots) were detected in the dendrites. Ca2+ spread from the center of hot spots wi...

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I whakaputaina i:	Proc Natl Acad Sci U S A
Ngā kaituhi matua:	Malinow, R, Otmakhov, N, Blum, K I, Lisman, J
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	National Academy of Sciences 1994
Ngā marau:	Research Article
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44567/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7914703/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.17.8170
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