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Poly(A) Polymerase and the Nuclear Poly(A) Binding Protein, PABPN1, Coordinate the Splicing and Degradation of a Subset of Human Pre-mRNAs

Most human protein-encoding transcripts contain multiple introns that are removed by splicing. Although splicing catalysis is frequently cotranscriptional, some introns are excised after polyadenylation. Accumulating evidence suggests that delayed splicing has regulatory potential, but the mechanism...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Muniz, Lisa, Davidson, Lee, West, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456446/
https://ncbi.nlm.nih.gov/pubmed/25896913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00123-15
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