Mefunidone Attenuates Tubulointerstitial Fibrosis in a Rat Model of Unilateral Ureteral Obstruction

BACKGROUND: Inflammation has a crucial role in renal interstitial fibrosis, which is the common pathway of chronic kidney diseases. Mefunidone (MFD) is a new compound which could effectively inhibit the proliferation of renal fibroblasts in vitro. However, the overall effect of Mefunidone in renal f...

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Vydáno v:PLoS One
Hlavní autoři: Liu, Chunyan, Mei, Wenjuan, Tang, Juan, Yuan, Qiongjing, Huang, Ling, Lu, Miaomiao, Wu, Lin, Peng, Zhangzhe, Meng, Jie, Yang, Huixiang, Shen, Hong, Lv, Ben, Hu, Gaoyun, Tao, Lijian
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456380/
https://ncbi.nlm.nih.gov/pubmed/26042668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129283
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