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Efficient estimation of three-dimensional covariance and its application in the analysis of heterogeneous samples in cryo-electron microscopy
Single-particle cryogenic electron microscopy (cryo-EM) is a powerful tool for the study of macromolecular structures at high resolution. Classification allows multiple structural states to be extracted and reconstructed from the same sample. One classification approach is via the covariance matrix,...
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| Published in: | Structure |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456258/ https://ncbi.nlm.nih.gov/pubmed/25982529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.04.004 |
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