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Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation
The AAA(+) ATPase Vps4 disassembles ESCRT-III and is essential for HIV-1 budding and other pathways. Vps4 is a paradigmatic member of a class of hexameric AAA(+) ATPases that disassemble protein complexes without degradation. To distinguish between local displacement versus global unfolding mechanis...
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| Foilsithe in: | Nat Struct Mol Biol |
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| Main Authors: | , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2015
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456219/ https://ncbi.nlm.nih.gov/pubmed/25938660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3015 |
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