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Repulsive Guidance Molecule is a structural bridge between Neogenin and Bone Morphogenetic Protein

Repulsive guidance molecules (RGMs) control crucial processes spanning cell motility, adhesion, immune cell regulation and systemic iron metabolism. RGMs signal via two fundamental signaling cascades: the Neogenin (NEO1) and the Bone Morphogenetic Protein (BMP) pathways. Here, we report crystal stru...

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Bibliografiske detaljer
Udgivet i:Nat Struct Mol Biol
Main Authors: Healey, Eleanor G., Bishop, Benjamin, Elegheert, Jonathan, Bell, Christian H., Padilla-Parra, Sergi, Siebold, Christian
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456160/
https://ncbi.nlm.nih.gov/pubmed/25938661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3016
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