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Therapeutic antibodies against CGRP or its receptor
CGRP is an extensively studied neuropeptide that has been implicated in the pathophysiology of migraine. While a number of small molecule antagonists against the CGRP receptor have demonstrated that targeting this pathway is a valid and effective way of treating migraine, off-target hepatoxicity and...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456121/ https://ncbi.nlm.nih.gov/pubmed/25614243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12591 |
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