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An In Vitro Model of Latency and Reactivation of Varicella Zoster Virus in Human Stem Cell-Derived Neurons

Varicella zoster virus (VZV) latency in sensory and autonomic neurons has remained enigmatic and difficult to study, and experimental reactivation has not yet been achieved. We have previously shown that human embryonic stem cell (hESC)-derived neurons are permissive to a productive and spreading VZ...

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發表在:PLoS Pathog
Main Authors: Markus, Amos, Lebenthal-Loinger, Ilana, Yang, In Hong, Kinchington, Paul R., Goldstein, Ronald S.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456082/
https://ncbi.nlm.nih.gov/pubmed/26042814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004885
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