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An In Vitro Model of Latency and Reactivation of Varicella Zoster Virus in Human Stem Cell-Derived Neurons

Varicella zoster virus (VZV) latency in sensory and autonomic neurons has remained enigmatic and difficult to study, and experimental reactivation has not yet been achieved. We have previously shown that human embryonic stem cell (hESC)-derived neurons are permissive to a productive and spreading VZ...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Markus, Amos, Lebenthal-Loinger, Ilana, Yang, In Hong, Kinchington, Paul R., Goldstein, Ronald S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456082/
https://ncbi.nlm.nih.gov/pubmed/26042814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004885
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