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Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies

The formulation and delivery of biopharmaceutical drugs, such as monoclonal antibodies and recombinant proteins, poses substantial challenges owing to their large size and susceptibility to degradation. In this Review we highlight recent advances in formulation and delivery strategies — such as the...

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Библиографические подробности
Опубликовано в: :Nat Rev Drug Discov
Главные авторы: Mitragotri, Samir, Burke, Paul A., Langer, Robert
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455970/
https://ncbi.nlm.nih.gov/pubmed/25103255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd4363
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