A conjugate of octamer-binding transcription factor 4 and toll-like receptor 7 agonist prevents the growth and metastasis of testis embryonic carcinoma

BACKGROUND: The immune non-recognition is often the underlying cause of failure in tumor immunotherapeutic. This is because most tumor-related antigens are poorly immunogenic, and fail to arouse an efficient immune response against cancers. Here we synthesized a novel TLR7 agonist, and developed a s...

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Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Lin, Guimiao, Wang, Xiaomei, Yi, Wanxian, Zhang, Chuanxia, Xu, Gaixia, Zhu, Xiaomei, Cai, Zhiming, Liu, Yu, Diao, Yuwen, Lin, Marie Chia-Mi, Jin, Guangyi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455914/
https://ncbi.nlm.nih.gov/pubmed/25990580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0524-y
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