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Restoration of Mitochondrial Gene Expression Using a Cloned Human Gene in Chinese Hamster Lung Cell Mutant
BACKGROUND: Gal(−)32 is a Chinese hamster lung cell nuclear mutant that is unable to grow in galactose due to a defect in mitochondrial protein synthesis. Since the product of the Gal(−)32 gene was unknown, it was imperative to use phenotypic complementation to clone a human gene that corrected the...
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| Publicado no: | Adv Tech Biol Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4455902/ https://ncbi.nlm.nih.gov/pubmed/26052559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2379-1764.1000120 |
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