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Benefits and harms of roflumilast in moderate to severe COPD

BACKGROUND: Roflumilast, a phosphodiesterase 4 inhibitor, was approved for the prevention of COPD exacerbations. It is unclear in which patients roflumilast will have a favorable benefit-harm balance. Our aim was to quantitatively assess the benefits and harms of roflumilast (500 mcg per day) compar...

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Detalhes bibliográficos
Publicado no:Thorax
Main Authors: Yu, Tsung, Fain, Kevin M., Boyd, Cynthia M., Singh, Sonal, Weiss, Carlos O., Li, Tianjing, Varadhan, Ravi, Puhan, Milo A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455881/
https://ncbi.nlm.nih.gov/pubmed/24347460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2013-204155
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