Ranitidine reduced levodopa-induced dyskinesia by remodeling neurochemical changes in hemiparkinsonian model of rats

BACKGROUND: Levodopa (l-dopa) remains the best drug in the treatment of Parkinson’s disease (PD). Unfortunately, long-term l-dopa caused motor complications, one of which is l-dopa-induced dyskinesia (LID). The precise mechanisms of LID are not fully understood. We have previously reported that rani...

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Bibliographische Detailangaben
Veröffentlicht in:Neuropsychiatr Dis Treat
Hauptverfasser: Shi, Hongjuan, Yang, Xinxin, Zhao, Hui, Zhang, Shenyang, Zu, Jie, Zhang, Wei, Shen, Xia, Cui, Guiyun, Hua, Fang, Yan, Chuanzhu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2015
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455849/
https://ncbi.nlm.nih.gov/pubmed/26064051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S80174
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