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Levodopa-induced plasticity: a double-edged sword in Parkinson's disease?

The long-term replacement therapy with the dopamine (DA) precursor 3,4-dihydroxy-l-phenylalanine (L-DOPA) is a milestone in the treatment of Parkinson's disease (PD). Although this drug precursor can be metabolized into the active neurotransmitter DA throughout the brain, its therapeutic benefi...

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Détails bibliographiques
Publié dans:Philos Trans R Soc Lond B Biol Sci
Auteurs principaux: Calabresi, Paolo, Ghiglieri, Veronica, Mazzocchetti, Petra, Corbelli, Ilenia, Picconi, Barbara
Format: Artigo
Langue:Inglês
Publié: The Royal Society 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455753/
https://ncbi.nlm.nih.gov/pubmed/26009763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0184
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