Multiple Sclerosis: Myeloperoxidase Immunoradiology Improves Detection of Acute and Chronic Disease in Experimental Model

PURPOSE: To test if MPO-Gd, a gadolinium-based magnetic resonance (MR) imaging probe that is sensitive and specific for the proinflammatory and oxidative enzyme myeloperoxidase (MPO), which is secreted by certain inflammatory cells, is more sensitive than diethylenetriaminepentaacetic acid (DTPA)-Gd...

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Bibliographic Details
Published in:Radiology
Main Authors: Pulli, Benjamin, Bure, Lionel, Wojtkiewicz, Gregory R., Iwamoto, Yoshiko, Ali, Muhammad, Li, Dan, Schob, Stefan, Hsieh, Kevin Li-Chun, Jacobs, Andreas H., Chen, John W.
Format: Artigo
Language:Inglês
Published: Radiological Society of North America 2015
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455671/
https://ncbi.nlm.nih.gov/pubmed/25494298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.14141495
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