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The HIF-1 inhibitor YC-1 decreases reactive astrocyte formation in a rodent ischemia model

Astrocytes become reactive after central nervous system injury, re-expressing glial fibrillary acidic protein (GFAP), vascular endothelial growth factor (VEGF), and nestin. Hypoxia-inducible transcription factor alpha (HIF-1α) is an important transcription factor for several genes including the VEGF...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Na, Jong-In, Na, Joo-Young, Choi, Woo-Young, Lee, Min-Cheol, Park, Man-Seok, Choi, Kang-Ho, Lee, Jeong-Kil, Kim, Kyung-Tae, Park, Jong-Tae, Kim, Hyung-Seok
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455349/
https://ncbi.nlm.nih.gov/pubmed/26064442
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