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Chitosan/siCkip-1 biofunctionalized titanium implant for improved osseointegration in the osteoporotic condition

Biofunctionalization with siRNA targeting the key negative modulators of bone turnover involved in the molecular mechanism of osteoporosis, such as casein kinase-2 interacting protein-1 (Ckip-1), may lead to enhanced Ti osseointegration in the osteoporotic condition. In this study, even siRNA loadin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Li, Wu, Kaimin, Song, Wen, Xu, Haiyan, An, Ran, Zhao, Lingzhou, Liu, Bin, Zhang, Yumei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455222/
https://ncbi.nlm.nih.gov/pubmed/26040545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10860
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