Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice

Heritable epigenetic factors can contribute to complex disease etiology. Here we examine the contribution of DNA methylation to complex traits that are precursors to heart disease, diabetes and osteoporosis. We profiled DNA methylation in the liver using bisulfite sequencing in 90 mouse inbred strai...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Orozco, Luz D., Morselli, Marco, Rubbi, Liudmilla, Guo, Weilong, Go, James, Shi, Huwenbo, Lopez, David, Furlotte, Nicholas A, Bennett, Brian J, Farber, Charles R, Ghazalpour, Anatole, Zhang, Michael Q, Bahous, Renata, Rozen, Rima, Lusis, Aldons J, Pellegrini, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454894/
https://ncbi.nlm.nih.gov/pubmed/26039453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.04.025
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