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Genetic and Epigenetic Modulation of Growth Hormone Sensitivity Studied With the IGF-1 Generation Test

CONTEXT: Like all hormones, GH has variable physiological effects across people. Many of these effects initiated by the binding of GH to its receptor (GHR) in target tissues are mediated by the expression of the IGF1 gene. Genetic as well as epigenetic variation is known to contribute to the individ...

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Detalles Bibliográficos
Publicado en:J Clin Endocrinol Metab
Main Authors: Ouni, Meriem, Castell, Anne-Laure, Linglart, Agnès, Bougnères, Pierre
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454803/
https://ncbi.nlm.nih.gov/pubmed/25835289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2015-1413
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