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Transcriptional Regulation via Nuclear Receptor Crosstalk Required for the Drosophila Circadian Clock

Circadian clocks in large part rely on transcriptional feedback loops. At the core of the clock machinery, the transcriptional activators CLOCK/BMAL1 (in mammals) and CLOCK/CYCLE (CLK/CYC) (in Drosophila) drive the expression of the period (per) family genes. The PER-containing complexes inhibit the...

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Detalles Bibliográficos
Publicado en:Curr Biol
Main Authors: Jaumouillé, Edouard, Machado Almeida, Pedro, Stähli, Patrick, Koch, Rafael, Nagoshi, Emi
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454776/
https://ncbi.nlm.nih.gov/pubmed/26004759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2015.04.017
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