Precursor Amino Acids Inhibit Polymyxin E Biosynthesis in Paenibacillus polymyxa, Probably by Affecting the Expression of Polymyxin E Biosynthesis-Associated Genes

Polymyxin E belongs to cationic polypeptide antibiotic bearing four types of direct precursor amino acids including L-2,4-diaminobutyric acid (L-Dab), L-Leu, D-Leu, and L-Thr. The objective of this study is to evaluate the effect of addition of precursor amino acids during fermentation on polymyxin...

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Bibliografische gegevens
Gepubliceerd in:Biomed Res Int
Hoofdauteurs: Yu, Zhiliang, Guo, Chenglin, Qiu, Juanping
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454717/
https://ncbi.nlm.nih.gov/pubmed/26078961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/690830
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