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Mcl-1 Is a Novel Target of miR-26b That Is Associated with the Apoptosis Induced by TRAIL in HCC Cells

Aim. To investigate the role of miR-26b and Mcl-1 in TRAIL-inducing cell death in hepatocellular carcinoma. Methods. The expression of miR-26b and Mcl-1 in HCC was detected by RT-qPCR and western blot. The regulation of Mcl-1 by miR-26b was determined by luciferase reporter assay. MTT and flow cytom...

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Detaylı Bibliyografya
Yayımlandı:Biomed Res Int
Asıl Yazarlar: Jiang, Chunlin, Long, Jianting, Liu, Baoxian, Xie, Xiaoyan, Kuang, Ming
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454716/
https://ncbi.nlm.nih.gov/pubmed/26078955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/572738
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