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Deregulated Expression of the Homeobox Gene Cux-1 in Transgenic Mice Results in Downregulation of p27(kip1) Expression during Nephrogenesis, Glomerular Abnormalities, and Multiorgan Hyperplasia

Cux-1 is a murine homeobox gene that is highly expressed in the developing kidney with expression restricted to the nephrogenic zone. Cux-1 is highly expressed in cyst epithelium of polycystic kidneys from C57BL/6J-cpk/cpk mice, but not in kidneys isolated from age-matched phenotypically normal litt...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Ledford, Aric W., Brantley, Jennifer G., Kemeny, Gabor, Foreman, Tonia L., Quaggin, Susan E., Igarashi, Peter, Oberhaus, Stephanie M., Rodova, Marianna, Calvet, James P., Heuvel, Gregory B. Vanden
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454426/
https://ncbi.nlm.nih.gov/pubmed/11969263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1006/dbio.2002.0636
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